Human HIPK2(Homeodomain Interacting Protein Kinase 2) ELISA Kit

Human HIPK2(Homeodomain Interacting Protein Kinase 2) ELISA Kit

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    Homeodomain Interacting Protein Kinase 2 (HIPK2) Antibody

    abx122745-100ug 100 ug
    EUR 391

    Homeodomain Interacting Protein Kinase 2 (HIPK2) Antibody

    20-abx128325
    • EUR 425.00
    • EUR 133.00
    • EUR 1205.00
    • EUR 578.00
    • EUR 328.00
    • 100 ug
    • 10 ug
    • 1 mg
    • 200 ug
    • 50 ug

    Homeodomain Interacting Protein Kinase 2 (HIPK2) Antibody

    20-abx124184
    • EUR 411.00
    • EUR 592.00
    • EUR 182.00
    • EUR 314.00
    • 100 ul
    • 200 ul
    • 20 ul
    • 50 ul

    Homeodomain Interacting Protein Kinase 2 (HIPK2) Antibody

    20-abx008183
    • EUR 300.00
    • EUR 439.00
    • EUR 189.00
    • 100 ul
    • 200 ul
    • 30 ul

    Homeodomain Interacting Protein Kinase 2 (HIPK2) Antibody

    abx033460-400ul 400 ul
    EUR 523

    Homeodomain Interacting Protein Kinase 2 (HIPK2) Antibody

    abx033460-80l 80 µl
    EUR 286

    Homeodomain Interacting Protein Kinase 2 (HIPK2) Antibody

    abx033461-400ul 400 ul
    EUR 523

    Homeodomain Interacting Protein Kinase 2 (HIPK2) Antibody

    abx033461-80l 80 µl
    EUR 286

    Homeodomain Interacting Protein Kinase 2 (HIPK2) Antibody

    20-abx215889
    • EUR 425.00
    • EUR 342.00
    • 100 ug
    • 50 ug

    Recombinant Homeodomain Interacting Protein Kinase 2 (HIPK2)

    4-RPF477Hu01
    • EUR 476.32
    • EUR 230.00
    • EUR 1511.20
    • EUR 570.40
    • EUR 1040.80
    • EUR 382.00
    • EUR 3628.00
    • 100 ug
    • 10ug
    • 1 mg
    • 200 ug
    • 500 ug
    • 50ug
    • 5 mg
    Description: Recombinant Human Homeodomain Interacting Protein Kinase 2 expressed in: E.coli

    Human Homeodomain Interacting Protein Kinase 2 (HIPK2) Protein

    20-abx166100
    • EUR 662.00
    • EUR 272.00
    • EUR 2040.00
    • EUR 787.00
    • EUR 481.00
    • 100 ug
    • 10 ug
    • 1 mg
    • 200 ug
    • 50 ug

    Mouse Homeodomain- interacting protein kinase 2, Hipk2 ELISA KIT

    ELI-14453m 96 Tests
    EUR 865

    Human Homeodomain Interacting Protein Kinase 2 (HIPK2) CLIA Kit

    20-abx494916
    • EUR 7973.00
    • EUR 4246.00
    • EUR 981.00
    • 10 × 96 tests
    • 5 × 96 tests
    • 96 tests

    ELISA kit for Human HIPK2 (Homeodomain Interacting Protein Kinase 2)

    ELK5068 1 plate of 96 wells
    EUR 432
    Description: A sandwich ELISA kit for detection of Homeodomain Interacting Protein Kinase 2 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

    Homeodomain Interacting Protein Kinase 2 (HIPK2) Polyclonal Antibody (Human)

    4-PAF477Hu01
    • EUR 247.00
    • EUR 2510.00
    • EUR 625.00
    • EUR 310.00
    • EUR 214.00
    • 100ul
    • 10ml
    • 1ml
    • 200ul
    • 20ul
    Description: A Rabbit polyclonal antibody against Human Homeodomain Interacting Protein Kinase 2 (HIPK2)

    Homeodomain Interacting Protein Kinase 2 (HIPK2) Polyclonal Antibody (Human), APC

    4-PAF477Hu01-APC
    • EUR 345.00
    • EUR 3275.00
    • EUR 912.00
    • EUR 440.00
    • EUR 219.00
    • 100ul
    • 10ml
    • 1ml
    • 200ul
    • 20ul
    Description: A Rabbit polyclonal antibody against Human Homeodomain Interacting Protein Kinase 2 (HIPK2). This antibody is labeled with APC.

    Homeodomain Interacting Protein Kinase 2 (HIPK2) Polyclonal Antibody (Human), Biotinylated

    4-PAF477Hu01-Biotin
    • EUR 311.00
    • EUR 2460.00
    • EUR 727.00
    • EUR 381.00
    • EUR 219.00
    • 100ul
    • 10ml
    • 1ml
    • 200ul
    • 20ul
    Description: A Rabbit polyclonal antibody against Human Homeodomain Interacting Protein Kinase 2 (HIPK2). This antibody is labeled with Biotin.

    Homeodomain Interacting Protein Kinase 2 (HIPK2) Polyclonal Antibody (Human), Cy3

    4-PAF477Hu01-Cy3
    • EUR 419.00
    • EUR 4325.00
    • EUR 1175.00
    • EUR 545.00
    • EUR 251.00
    • 100ul
    • 10ml
    • 1ml
    • 200ul
    • 20ul
    Description: A Rabbit polyclonal antibody against Human Homeodomain Interacting Protein Kinase 2 (HIPK2). This antibody is labeled with Cy3.

    Homeodomain Interacting Protein Kinase 2 (HIPK2) Polyclonal Antibody (Human), FITC

    4-PAF477Hu01-FITC
    • EUR 296.00
    • EUR 2640.00
    • EUR 750.00
    • EUR 372.00
    • EUR 195.00
    • 100ul
    • 10ml
    • 1ml
    • 200ul
    • 20ul
    Description: A Rabbit polyclonal antibody against Human Homeodomain Interacting Protein Kinase 2 (HIPK2). This antibody is labeled with FITC.

    Homeodomain Interacting Protein Kinase 2 (HIPK2) Polyclonal Antibody (Human), HRP

    4-PAF477Hu01-HRP
    • EUR 316.00
    • EUR 2855.00
    • EUR 807.00
    • EUR 398.00
    • EUR 206.00
    • 100ul
    • 10ml
    • 1ml
    • 200ul
    • 20ul
    Description: A Rabbit polyclonal antibody against Human Homeodomain Interacting Protein Kinase 2 (HIPK2). This antibody is labeled with HRP.

    Homeodomain Interacting Protein Kinase 2 (HIPK2) Polyclonal Antibody (Human), PE

    4-PAF477Hu01-PE
    • EUR 296.00
    • EUR 2640.00
    • EUR 750.00
    • EUR 372.00
    • EUR 195.00
    • 100ul
    • 10ml
    • 1ml
    • 200ul
    • 20ul
    Description: A Rabbit polyclonal antibody against Human Homeodomain Interacting Protein Kinase 2 (HIPK2). This antibody is labeled with PE.

    Homeodomain Interacting Protein Kinase 2 (HIPK2) Polyclonal Antibody (Human), APC-Cy7

    4-PAF477Hu01-APC-Cy7
    • EUR 571.00
    • EUR 6430.00
    • EUR 1705.00
    • EUR 760.00
    • EUR 319.00
    • 100ul
    • 10ml
    • 1ml
    • 200ul
    • 20ul
    Description: A Rabbit polyclonal antibody against Human Homeodomain Interacting Protein Kinase 2 (HIPK2). This antibody is labeled with APC-Cy7.

    Recombinant human Homeodomain-interacting protein kinase 2

    P2714 100ug Ask for price
    Description: Recombinant protein for human Homeodomain-interacting protein kinase 2

    Human Homeodomain- interacting protein kinase 4, HIPK4 ELISA KIT

    ELI-48104h 96 Tests
    EUR 824

    Human Homeodomain- interacting protein kinase 1, HIPK1 ELISA KIT

    ELI-08581h 96 Tests
    EUR 824

    Human Homeodomain- interacting protein kinase 3, HIPK3 ELISA KIT

    ELI-14454h 96 Tests
    EUR 824

    Mouse Homeodomain- interacting protein kinase 3, Hipk3 ELISA KIT

    ELI-31408m 96 Tests
    EUR 865

    Mouse Homeodomain- interacting protein kinase 4, Hipk4 ELISA KIT

    ELI-27829m 96 Tests
    EUR 865

    Mouse Homeodomain- interacting protein kinase 1, Hipk1 ELISA KIT

    ELI-20333m 96 Tests
    EUR 865

    Human Homeodomain Interacting Protein Kinase 1 (HIPK1) Protein

    20-abx650018
    • EUR 662.00
    • EUR 272.00
    • EUR 2040.00
    • EUR 787.00
    • EUR 481.00
    • 100 ug
    • 10 ug
    • 1 mg
    • 200 ug
    • 50 ug

    Homeodomain Interacting Protein Kinase 1 (HIPK1) Antibody

    20-abx131354
    • EUR 425.00
    • EUR 133.00
    • EUR 1205.00
    • EUR 578.00
    • EUR 328.00
    • 100 ug
    • 10 ug
    • 1 mg
    • 200 ug
    • 50 ug

    Homeodomain-Interacting Protein Kinase 4 (HIPK4) Antibody

    20-abx013698
    • EUR 314.00
    • EUR 98.00
    • EUR 398.00
    • EUR 495.00
    • 100 ug
    • 10 ug
    • 200 ug
    • 300 µg

    Homeodomain Interacting Protein Kinase 1 (HIPK1) Antibody

    abx026832-400ul 400 ul
    EUR 523

    Homeodomain Interacting Protein Kinase 1 (HIPK1) Antibody

    abx026832-80l 80 µl
    EUR 286

    Homeodomain-Interacting Protein Kinase 4 (HIPK4) Antibody

    abx027094-400ul 400 ul
    EUR 523

    Homeodomain-Interacting Protein Kinase 4 (HIPK4) Antibody

    abx027094-80l 80 µl
    EUR 286

    Homeodomain-Interacting Protein Kinase 4 (HIPK4) Antibody

    abx033195-400ul 400 ul
    EUR 523

    Homeodomain-Interacting Protein Kinase 4 (HIPK4) Antibody

    abx033195-80l 80 µl
    EUR 286

    Homeodomain Interacting Protein Kinase 3 (HIPK3) Antibody

    20-abx215890
    • EUR 425.00
    • EUR 342.00
    • 100 ug
    • 50 ug

    Homeodomain Interacting Protein Kinase 1 (HIPK1) Antibody

    abx145234-100ug 100 ug
    EUR 391

    Homeodomain-Interacting Protein Kinase 4 (HIPK4) Antibody

    abx145598-100ug 100 ug
    EUR 391

    Homeodomain Interacting Protein Kinase 4 (HIPK4) Antibody

    20-abx241229
    • EUR 411.00
    • EUR 300.00
    • 100 ul
    • 50 ul

    Homeodomain Interacting Protein Kinase 1 (HIPK1) Antibody

    20-abx213865
    • EUR 411.00
    • EUR 300.00
    • 100 ul
    • 50 ul

    Homeodomain Interacting Protein Kinase 1 (HIPK1) Antibody

    20-abx213933
    • EUR 411.00
    • EUR 300.00
    • 100 ul
    • 50 ul

    Homeodomain Interacting Protein Kinase 4 (HIPK4) Antibody

    20-abx214584
    • EUR 411.00
    • EUR 300.00
    • 100 ul
    • 50 ul

    Homeodomain Interacting Protein Kinase 4 (HIPK4) Antibody

    20-abx329371
    • EUR 314.00
    • EUR 244.00
    • 100 ug
    • 50 ug

    Homeodomain Interacting Protein Kinase 4 (HIPK4) Antibody

    abx332361-100ul 100 ul
    EUR 425

    Homeodomain Interacting Protein Kinase 1 (HIPK1) Antibody

    20-abx334178
    • EUR 411.00
    • EUR 1845.00
    • EUR 599.00
    • EUR 182.00
    • EUR 300.00
    • 100 ug
    • 1 mg
    • 200 ug
    • 20 ug
    • 50 ug

    Homeodomain Interacting Protein Kinase 3 (HIPK3) Antibody

    20-abx333862
    • EUR 411.00
    • EUR 1845.00
    • EUR 599.00
    • EUR 182.00
    • EUR 300.00
    • 100 ug
    • 1 mg
    • 200 ug
    • 20 ug
    • 50 ug

    Recombinant Homeodomain Interacting Protein Kinase 4 (HIPK4)

    4-RPF475Hu01
    • EUR 413.60
    • EUR 214.00
    • EUR 1276.00
    • EUR 492.00
    • EUR 884.00
    • EUR 340.00
    • EUR 3040.00
    • 100 ug
    • 10ug
    • 1 mg
    • 200 ug
    • 500 ug
    • 50ug
    • 5 mg
    Description: Recombinant Human Homeodomain Interacting Protein Kinase 4 expressed in: E.coli

    Recombinant Homeodomain Interacting Protein Kinase 3 (HIPK3)

    4-RPF476Hu01
    • EUR 413.60
    • EUR 214.00
    • EUR 1276.00
    • EUR 492.00
    • EUR 884.00
    • EUR 340.00
    • EUR 3040.00
    • 100 ug
    • 10ug
    • 1 mg
    • 200 ug
    • 500 ug
    • 50ug
    • 5 mg
    Description: Recombinant Human Homeodomain Interacting Protein Kinase 3 expressed in: E.coli

    Recombinant Homeodomain Interacting Protein Kinase 3 (HIPK3)

    4-RPF476Mu01
    • EUR 449.44
    • EUR 223.00
    • EUR 1410.40
    • EUR 536.80
    • EUR 973.60
    • EUR 364.00
    • EUR 3376.00
    • 100 ug
    • 10ug
    • 1 mg
    • 200 ug
    • 500 ug
    • 50ug
    • 5 mg
    Description: Recombinant Mouse Homeodomain Interacting Protein Kinase 3 expressed in: E.coli

    Recombinant Homeodomain Interacting Protein Kinase 1 (HIPK1)

    4-RPC526Hu01
    • EUR 476.32
    • EUR 230.00
    • EUR 1511.20
    • EUR 570.40
    • EUR 1040.80
    • EUR 382.00
    • EUR 3628.00
    • 100 ug
    • 10ug
    • 1 mg
    • 200 ug
    • 500 ug
    • 50ug
    • 5 mg
    Description: Recombinant Human Homeodomain Interacting Protein Kinase 1 expressed in: E.coli

    Homeodomain Interacting Protein Kinase 1 (HIPK1) Polyclonal Antibody (Human)

    4-PAC526Hu01
    • EUR 247.00
    • EUR 2510.00
    • EUR 625.00
    • EUR 310.00
    • EUR 214.00
    • 100ul
    • 10ml
    • 1ml
    • 200ul
    • 20ul
    Description: A Rabbit polyclonal antibody against Human Homeodomain Interacting Protein Kinase 1 (HIPK1)

    Homeodomain Interacting Protein Kinase 1 (HIPK1) Antibody (HRP)

    20-abx336060
    • EUR 411.00
    • EUR 1845.00
    • EUR 599.00
    • EUR 182.00
    • EUR 300.00
    • 100 ug
    • 1 mg
    • 200 ug
    • 20 ug
    • 50 ug

    Homeodomain Interacting Protein Kinase 1 (HIPK1) Antibody (FITC)

    20-abx336061
    • EUR 411.00
    • EUR 1845.00
    • EUR 599.00
    • EUR 182.00
    • EUR 300.00
    • 100 ug
    • 1 mg
    • 200 ug
    • 20 ug
    • 50 ug

    Homeodomain Interacting Protein Kinase 1 (HIPK1) Antibody (Biotin)

    20-abx336062
    • EUR 411.00
    • EUR 1845.00
    • EUR 599.00
    • EUR 182.00
    • EUR 300.00
    • 100 ug
    • 1 mg
    • 200 ug
    • 20 ug
    • 50 ug

    Homeodomain Interacting Protein Kinase 3 (HIPK3) Antibody (HRP)

    20-abx336063
    • EUR 411.00
    • EUR 1845.00
    • EUR 599.00
    • EUR 182.00
    • EUR 300.00
    • 100 ug
    • 1 mg
    • 200 ug
    • 20 ug
    • 50 ug

    Homeodomain Interacting Protein Kinase 3 (HIPK3) Antibody (FITC)

    20-abx336064
    • EUR 411.00
    • EUR 1845.00
    • EUR 599.00
    • EUR 182.00
    • EUR 300.00
    • 100 ug
    • 1 mg
    • 200 ug
    • 20 ug
    • 50 ug

    Homeodomain Interacting Protein Kinase 3 (HIPK3) Antibody (Biotin)

    20-abx336065
    • EUR 411.00
    • EUR 1845.00
    • EUR 599.00
    • EUR 182.00
    • EUR 300.00
    • 100 ug
    • 1 mg
    • 200 ug
    • 20 ug
    • 50 ug

    Homeodomain Interacting Protein Kinase 1 (HIPK1) Polyclonal Antibody (Human), APC

    4-PAC526Hu01-APC
    • EUR 345.00
    • EUR 3275.00
    • EUR 912.00
    • EUR 440.00
    • EUR 219.00
    • 100ul
    • 10ml
    • 1ml
    • 200ul
    • 20ul
    Description: A Rabbit polyclonal antibody against Human Homeodomain Interacting Protein Kinase 1 (HIPK1). This antibody is labeled with APC.

    Homeodomain Interacting Protein Kinase 1 (HIPK1) Polyclonal Antibody (Human), Biotinylated

    4-PAC526Hu01-Biotin
    • EUR 311.00
    • EUR 2460.00
    • EUR 727.00
    • EUR 381.00
    • EUR 219.00
    • 100ul
    • 10ml
    • 1ml
    • 200ul
    • 20ul
    Description: A Rabbit polyclonal antibody against Human Homeodomain Interacting Protein Kinase 1 (HIPK1). This antibody is labeled with Biotin.

    Homeodomain Interacting Protein Kinase 1 (HIPK1) Polyclonal Antibody (Human), Cy3

    4-PAC526Hu01-Cy3
    • EUR 419.00
    • EUR 4325.00
    • EUR 1175.00
    • EUR 545.00
    • EUR 251.00
    • 100ul
    • 10ml
    • 1ml
    • 200ul
    • 20ul
    Description: A Rabbit polyclonal antibody against Human Homeodomain Interacting Protein Kinase 1 (HIPK1). This antibody is labeled with Cy3.

    Homeodomain Interacting Protein Kinase 1 (HIPK1) Polyclonal Antibody (Human), FITC

    4-PAC526Hu01-FITC
    • EUR 296.00
    • EUR 2640.00
    • EUR 750.00
    • EUR 372.00
    • EUR 195.00
    • 100ul
    • 10ml
    • 1ml
    • 200ul
    • 20ul
    Description: A Rabbit polyclonal antibody against Human Homeodomain Interacting Protein Kinase 1 (HIPK1). This antibody is labeled with FITC.

    Homeodomain Interacting Protein Kinase 1 (HIPK1) Polyclonal Antibody (Human), HRP

    4-PAC526Hu01-HRP
    • EUR 316.00
    • EUR 2855.00
    • EUR 807.00
    • EUR 398.00
    • EUR 206.00
    • 100ul
    • 10ml
    • 1ml
    • 200ul
    • 20ul
    Description: A Rabbit polyclonal antibody against Human Homeodomain Interacting Protein Kinase 1 (HIPK1). This antibody is labeled with HRP.

    Homeodomain Interacting Protein Kinase 1 (HIPK1) Polyclonal Antibody (Human), PE

    4-PAC526Hu01-PE
    • EUR 296.00
    • EUR 2640.00
    • EUR 750.00
    • EUR 372.00
    • EUR 195.00
    • 100ul
    • 10ml
    • 1ml
    • 200ul
    • 20ul
    Description: A Rabbit polyclonal antibody against Human Homeodomain Interacting Protein Kinase 1 (HIPK1). This antibody is labeled with PE.

    Homeodomain Interacting Protein Kinase 1 (HIPK1) Polyclonal Antibody (Human), APC-Cy7

    4-PAC526Hu01-APC-Cy7
    • EUR 571.00
    • EUR 6430.00
    • EUR 1705.00
    • EUR 760.00
    • EUR 319.00
    • 100ul
    • 10ml
    • 1ml
    • 200ul
    • 20ul
    Description: A Rabbit polyclonal antibody against Human Homeodomain Interacting Protein Kinase 1 (HIPK1). This antibody is labeled with APC-Cy7.

    HIPK2 ELISA Kit (Human) (OKCD00468)

    OKCD00468 96 Wells
    EUR 831
    Description: Description of target: Serine/threonine-protein kinase involved in transcription regulation, p53/TP53-mediated cellular apoptosis and regulation of the cell cycle. Acts as a corepressor of several transcription factors, including SMAD1 and POU4F1/Brn3a and probably NK homeodomain transcription factors. Phosphorylates PDX1, ATF1, PML, p53/TP53, CREB1, CTBP1, CBX4, RUNX1, EP300, CTNNB1, HMGA1 and ZBTB4. Inhibits cell growth and promotes apoptosis through the activation of p53/TP53 both at the transcription level and at the protein level (by phosphorylation and indirect acetylation). The phosphorylation of p53/TP53 may be mediated by a p53/TP53-HIPK2-AXIN1 complex. Involved in the response to hypoxia by acting as a transcriptional co-suppressor of HIF1A. Mediates transcriptional activation of TP73. In response to TGFB, cooperates with DAXX to activate JNK. Negative regulator through phosphorylation and subsequent proteasomal degradation of CTNNB1 and the antiapoptotic factor CTBP1. In the Wnt/beta-catenin signaling pathway acts as an intermediate kinase between MAP3K7/TAK1 and NLK to promote the proteasomal degradation of MYB. Phosphorylates CBX4 upon DNA damage and promotes its E3 SUMO-protein ligase activity. Activates CREB1 and ATF1 transcription factors by phosphorylation in response to genotoxic stress. In response to DNA damage, stabilizes PML by phosphorylation. PML, HIPK2 and FBXO3 may act synergically to activate p53/TP53-dependent transactivation. Promotes angiogenesis, and is involved in erythroid differentiation, especially during fetal liver erythropoiesis. Phosphorylation of RUNX1 and EP300 stimulates EP300 transcription regulation activity. Triggers ZBTB4 protein degradation in response to DNA damage. Modulates HMGA1 DNA-binding affinity. In response to high glucose, triggers phosphorylation-mediated subnuclear localization shifting of PDX1. Involved in the regulation of eye size, lens formation and retinal lamination during late embryogenesis.18 Publications <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More…</a></p> Manual assertion based on experiment iniRef.8"Identification and characterization of HIPK2 interacting with p73 and modulating functions of the p53 family in vivo."_x005F_x005F_x000D_Kim E.-J., Park J.-S., Um S.-J._x005F_x005F_x000D_J. Biol. Chem. 277:32020-32028(2002) [PubMed] [Europe PMC] [Abstract]Cited for: INTERACTION WITH TP73; TP53 AND TP63, MUTAGENESIS OF LYS-228, FUNCTION.Ref.9"Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2."_x005F_x005F_x000D_Hofmann T.G., Moeller A., Sirma H., Zentgraf H., Taya Y., Droege W., Will H., Schmitz M.L._x005F_x005F_x000D_Nat. Cell Biol. 4:1-10(2002) [PubMed] [Europe PMC] [Abstract]Cited for: SUBCELLULAR LOCATION, AUTOPHOSPHORYLATION, INTERACTION WITH TP53 AND CREBBP, MUTAGENESIS OF LYS-228, FUNCTION, INDUCTION.Ref.11"HIPK2 regulates transforming growth factor-beta-induced c-Jun NH(2)-terminal kinase activation and apoptosis in human hepatoma cells."_x005F_x005F_x000D_Hofmann T.G., Stollberg N., Schmitz M.L., Will H._x005F_x005F_x000D_Cancer Res. 63:8271-8277(2003) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, INTERACTION WITH DAXX, MUTAGENESIS OF LYS-228.Ref.12"TP53INP1s and homeodomain-interacting protein kinase-2 (HIPK2) are partners in regulating p53 activity."_x005F_x005F_x000D_Tomasini R., Samir A.A., Carrier A., Isnardon D., Cecchinelli B., Soddu S., Malissen B., Dagorn J.-C., Iovanna J.L., Dusetti N.J._x005F_x005F_x000D_J. Biol. Chem. 278:37722-37729(2003) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, SUBCELLULAR LOCATION, INTERACTION WITH P53DINP1.Ref.13"Requirement of the co-repressor homeodomain-interacting protein kinase 2 for ski-mediated inhibition of bone morphogenetic protein-induced transcriptional activation."_x005F_x005F_x000D_Harada J., Kokura K., Kanei-Ishii C., Nomura T., Khan M.M., Kim Y., Ishii S._x005F_x005F_x000D_J. Biol. Chem. 278:38998-39005(2003) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, INTERACTION WITH SKI; SMAD1; SMAD2 AND SMAD3, MUTAGENESIS OF LYS-228 AND 359-SER--TYR-361.Ref.17"Phosphorylation-dependent control of Pc2 SUMO E3 ligase activity by its substrate protein HIPK2."_x005F_x005F_x000D_Roscic A., Moeller A., Calzado M.A., Renner F., Wimmer V.C., Gresko E., Luedi K.S., Schmitz M.L._x005F_x005F_x000D_Mol. Cell 24:77-89(2006) [PubMed] [Europe PMC] [Abstract]Cited for: INTERACTION WITH CBX4, SUMOYLATION AT LYS-32, FUNCTION.Ref.18"Homeodomain-interacting protein kinase-2 (HIPK2) phosphorylates HMGA1a at Ser-35, Thr-52, and Thr-77 and modulates its DNA binding affinity."_x005F_x005F_x000D_Zhang Q., Wang Y._x005F_x005F_x000D_J. Proteome Res. 6:4711-4719(2007) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION AS HMGA1 KINASE.Ref.19"PEBP2-beta/CBF-beta-dependent phosphorylation of RUNX1 and p300 by HIPK2: implications for leukemogenesis."_x005F_x005F_x000D_Wee H.-J., Voon D.C.-C., Bae S.-C., Ito Y._x005F_x005F_x000D_Blood 112:3777-3787(2008) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION AS RUNX1 AND EP300 KINASE, MUTAGENESIS OF LYS-228.Ref.21"PML activates transcription by protecting HIPK2 and p300 from SCFFbx3-mediated degradation."_x005F_x005F_x000D_Shima Y., Shima T., Chiba T., Irimura T., Pandolfi P.P., Kitabayashi I._x005F_x005F_x000D_Mol. Cell. Biol. 28:7126-7138(2008) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, UBIQUITINATION BY FBXO3.Ref.23"Transcriptional regulation of hypoxia-inducible factor 1alpha by HIPK2 suggests a novel mechanism to restrain tumor growth."_x005F_x005F_x000D_Nardinocchi L., Puca R., Guidolin D., Belloni A.S., Bossi G., Michiels C., Sacchi A., Onisto M., D'Orazi G._x005F_x005F_x000D_Biochim. Biophys. Acta 1793:368-377(2009) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION AS HIF1A TRANSCRIPTION REGULATOR AND ANGIOGENESIS PROMOTER.Ref.25"PML tumor suppressor is regulated by HIPK2-mediated phosphorylation in response to DNA damage."_x005F_x005F_x000D_Gresko E., Ritterhoff S., Sevilla-Perez J., Roscic A., Froebius K., Kotevic I., Vichalkovski A., Hess D., Hemmings B.A., Schmitz M.L._x005F_x005F_x000D_Oncogene 28:698-708(2009) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION AS PML KINASE, INTERACTION WITH PML, MUTAGENESIS OF LYS-228.Ref.26"The human protein kinase HIPK2 phosphorylates and downregulates the methyl-binding transcription factor ZBTB4."_x005F_x005F_x000D_Yamada D., Perez-Torrado R., Filion G., Caly M., Jammart B., Devignot V., Sasai N., Ravassard P., Mallet J., Sastre-Garau X., Schmitz M.L., Defossez P.A._x005F_x005F_x000D_Oncogene 28:2535-2544(2009) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION AS ZBTB4 KINASE, INTERACTION WITH ZBTB4.Ref.28"Pancreatic and duodenal homeobox 1 (PDX1) phosphorylation at serine-269 is HIPK2-dependent and affects PDX1 subnuclear localization."_x005F_x005F_x000D_An R., da Silva Xavier G., Semplici F., Vakhshouri S., Hao H.X., Rutter J., Pagano M.A., Meggio F., Pinna L.A., Rutter G.A._x005F_x005F_x000D_Biochem. Biophys. Res. Commun. 399:155-161(2010) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION AS PDX1 KINASE.Ref.29"Homeodomain-interacting protein kinase 2 (HIPK2) targets beta-catenin for phosphorylation and proteasomal degradation."_x005F_x005F_x000D_Kim E.-A., Kim J.E., Sung K.S., Choi D.W., Lee B.J., Choi C.Y._x005F_x005F_x000D_Biochem. Biophys. Res. Commun. 394:966-971(2010) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION AS CTNNB1 KINASE.Ref.30"Transcriptional regulation of ferritin and antioxidant genes by HIPK2 under genotoxic stress."_x005F_x005F_x000D_Hailemariam K., Iwasaki K., Huang B.W., Sakamoto K., Tsuji Y._x005F_x005F_x000D_J. Cell Sci. 123:3863-3871(2010) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION AS ATF1 KINASE, INTERACTION WITH ATF1.Ref.31"Regulation of genotoxic stress response by homeodomain-interacting protein kinase 2 through phosphorylation of cyclic AMP response element-binding protein at serine 271."_x005F_x005F_x000D_Sakamoto K., Huang B.-W., Iwasaki K., Hailemariam K., Ninomiya-Tsuji J., Tsuji Y._x005F_x005F_x000D_Mol. Biol. Cell 21:2966-2974(2010) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION AS CREB1 KINASE, INTERACTION WITH CREB1.Ref.33"Role of the SUMO-interacting motif in HIPK2 targeting to the PML nuclear bodies and regulation of p53."_x005F_x005F_x000D_Sung K.S., Lee Y.A., Kim E.T., Lee S.R., Ahn J.H., Choi C.Y._x005F_x005F_x000D_Exp. Cell Res. 317:1060-1070(2011) [PubMed] [Europe PMC] [Abstract]Cited for: SUBCELLULAR LOCATION, SUMOYLATION, FUNCTION, MUTAGENESIS OF 885-VAL--ILE-888 AND 892-SER--ASP-895.Ref.38"DNA damage-induced heterogeneous nuclear ribonucleoprotein K SUMOylation regulates p53 transcriptional activation."_x005F_x005F_x000D_Pelisch F., Pozzi B., Risso G., Munoz M.J., Srebrow A._x005F_x005F_x000D_J. Biol. Chem. 287:30789-30799(2012) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION. ;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 0.061 ng/mL

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